Supriya Jindal

ABOUT ME

Hi, I am a freelance medical and health science writer with a PhD in Molecular Biology. During my 10 years of academic experience (as a researcher and an instructor), I developed a passion for science communication.

My strong technical background coupled with logical thinking, and a detail-oriented approach helps me translate complex biological concepts to an easy-to-understand format.

If you need compelling, accurate and crisp solutions to your medical and health communication projects, contact me at [email protected].

PhD Thesis: Role of ribosomal molecule uS9 in translation initiation and elongation

 

Summary

  • Proteins are the workhorses of the cell. They perform a wide range of functions from product manufacture to breakdown, and recycle.
  • They are synthesized by specialized machinery called ribosomes—made of hundreds of molecules, many of whose functions remain unknown.
  • I studied the role of one such ribosomal molecule called uS9 in yeast Saccharomyces cerevisiae.
  • My research showed that uS9’s tail is important for initiating protein synthesis (translation). It also ensures accurate protein synthesis during translation elongation phase. This work was published in 2019, Nucleic Acids Research (IF: 14.9).
Ribosomal protein
Ribosome structure and function

My doctrol training was in the laboratory of Dr. Anton A. Komar at Center for Gene Regulation in Health and Disease, Cleveland State University, Oh. Below is the list of my publications in peer-reviewed journals:

Supriya Jindal, Arnab Ghosh, Amra Ismail, Nishant Singh, Anton A Komar
Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae
Nucleic Acids Research, Volume 47, January 2019, Pages 806–823.

Nishant Singh, Supriya Jindal, Arnab Ghosh, Anton A Komar
Communication between RACK1/Asc1 and uS3 (Rps3) is essential for RACK1/Asc1 function in yeast Saccharomyces cerevisiae
Gene, Volume 706, July 2019, Pages 69-76.

Lamis Yehia, Supriya Jindal, Anton A Komar, Charis Eng
Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway
Human Molecular Genetics, Volume 27, September 2018, Pages 3154–3164.

Alexandra Zinoviev, Akanksha Goyal, Supriya Jindal, John LaCava, Anton A. Komar, Marina V. Rodnina, Christopher U.T. Hellen and Tatyana V. Pestova.
Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2.
Genes and Development, Volume 32, September 2018, Pages 1226-1241.

Arnab Ghosh, Supriya Jindal, Amber A Bentley, Alan G Hinnebusch, Anton A Komar
Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae.
Nucleic Acids Research, Volume 42, July 2014, Pages 8537-8555.

Supriya Jindal, Aabgeena Naeem
Consequential secondary structure alterations and aggregation during prolonged casein glycation
Journal of Fluorescence, Volume 23, May 2013, Pages 367-374.